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46 However, a switch study examining triple therapy with exenatide, sitagliptin, and metformin found a clinically insignificant additional lowering of A1C (0.3%) after 20 weeks of follow-up

Indeed, dulaglutide shows sex-specific treatment differences, as males reduce their intake levels more than females, and the treatment effect persists after discontinuation in males but not in females (Vallof et al., 2020)

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Abbreviations LR: Liver resection GLP-1: Glucagon-like peptide-1 GLP-2: Glucagon-like peptide-2 PHLF: Post-hepatectomy liver failure IL-6: Interleukin-6 MASLD: Metabolic dysfunction-associated liver disease HDLc: High-density lipoprotein cholesterol LDLc: Low-density lipoprotein cholesterol VLDL: Very low-density lipoprotein ApoA1: Apolipoprotein A1 ApoB: Apolipoprotein B DPP4: Dipeptidyl peptidase 4 AUC: Area under the curve References Sparrelid, E