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Up-regulation of peroxisome proliferator-activated receptors (PPAR) and PPAR messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-responsive adipose tissue-specific genes in the liver of obese diabetic mice

However, fibroids can persist or occasionally develop post-menopausally when driven by other factors: aromatase activity in adipose tissue, maintaining estrogen production, exogenous hormone therapy, chronic low-grade inflammation, or insulin dysregulation

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