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NMR-based metabolomics data analysis 2D HSQC and TOCSY spectra were uploaded to the new COLMARq web server ( for peak picking, peak alignment, metabolite identification, metabolite quantification via Gaussian peak fitting, spectral normalization via global scaling based on the average, median 30% peak volume ratios between an arbitrarily selected reference spectrum, and univariate statistical analysis between cohorts (51, 52)

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Non-GLP-1 Medications: The platform also describes access to non-GLP-1 options including Contrave (bupropion-naltrexone), metformin , topiramate , and zonisamide - medications that target different mechanisms related to appetite, cravings, blood sugar regulation, and metabolic function