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Additionally, the risk of polyuria escalates in patients with low initial urine osmolarities or inadequate prior solute intake, necessitating meticulous solute and fluid management

Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW: Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

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