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However, patience is key, as the journey is gradual and requires consistent, positive changes to both medication adherence and lifestyle habits

10.1038/nrendo.2012.140 30

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La descarboxilacin del cido pirvico pasa por las etapas de piruvato activo y acetaldehdo activo y finalmente, mediante la intervencin del cido tictico o cido lipoico, se llega a la acetilacin de la coenzima A para producir la acetil coenzima A, substancia de gran importancia biolgica en el metabolismo oxidativo de los carbohidratos, especialmente en el ciclo de Krebs