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Significant weight loss was seen early on and was maintained out to 12 months in those that were compliant, and weight loss was significantly less pronounced in those patients that discontinued liraglutide prematurely

This pathological state creates an imbalance where ROS and RNS production exceeds the neutralizing ability of intrinsic antioxidant systems, thereby establishing conditions of oxidative stress (Rahman and MacNee, 2000)

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