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10.1016/j.ijbiomac.2024.136828 187 WuY.LiP.JiangZ.SunX.HeH.YanP.et al (2023)

, Highly palatable diet consumption increases protein oxidation in rat frontal cortex and anxiety-like behavior

Specifically, we tested the prevalent but unsubstantiated hypothesis that peripheral GLP-1 signals to the brain to suppress eating via vagal and/or endocrine activation of central GLP-1-producing preproglucagon (PPG) neurons, i.e

Practical Implications of the Research For the millions of Americans now using GLP-1 drugs, and the many who have already stopped, these findings offer a more nuanced picture than the trial data alone