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this, in turn, resulted in the upregulated expression of telomere repeat-binding factor 1/2 (TRF1/TRF2) proteins and strict dependence on p53/p21 signaling, followed by irreversible G2/M cell cycle arrest, ultimately leading to apoptosis

NCI 1R01CA193842-01, 1R01CA193842-06A1, 5R01CA186702-07, 1R01DK1010989-06A1, R01HL135564 and R01CA225231-01

The level of OGD-induced ferroptosis in ADSCs was assessed according to the viability of cells treated with the ferroptosis inhibitor Ferrostatin-1 (Fer-1) 5 M, autophagy inhibitor 3-Methyladenine (3-MA) 5 mM, apoptosis inhibitor Z-VAD-FMK 10 M, necroptosis inhibitor Necrostatin-1 (Nec-1) 50 M, or ferroptosis activator erastin

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