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However, as an increasing body of evidence demonstrates that paracrine interactions between alpha-cells and beta-cells are essential for the coordination of insulin secretion in vivo , it follows, therefore, that this paracrine crosstalk is also essential for the beneficial metabolic effects of pharmaceutical agents in vivo

Glucagon-like peptide-1 and its class B G proteincoupled receptors: a long march to therapeutic successes

In recent years, peptidesspecifically BPC-157 and TB-500 have gained attention for their impressive regenerative and healing properties

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