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In light of the restriction on the importation of biotechnological APIs and given the lack of effective enforcement by ANVISA, which suffers from staffing shortages, it is foreseeable - and has already been observed - that clinics are directing their activities almost exclusively to tirzepatide and the situation is likely to worsen

This timeline indicates that the first cases may reach juries by late 2026 or early 2027, though the pace could accelerate if settlement negotiations gain momentum after key pretrial rulings

The before and after timeline in this article is based on general clinical literature for patients researching all GH-releasing peptide options

Leg cramps are not listed as a recognised adverse effect in the UK Summaries of Product Characteristics (SmPCs) for GLP-1 receptor agonists, and evidence for a causal link is limited