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Under normal conditions, System Xc, composed of the functional subunit SLC7A11 and the regulatory subunit SLC3A2, facilitates the exchange of extracellular cystine for intracellular glutamate, ensuring a sufficient supply of GSH precursors (82)

They usually start with high doses and then lower them for maintenance

They are referred to as vitamers having vitamin activity as a coenzyme, meaning that its presence is required for some enzyme-catalyzed reactions