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Constipation : Bifidobacterium lactis BB-12 has been shown to improve bowel regularity and stool consistency 14 , potentially counteracting constipation

The detrimental effects of B12 deficiencysuch as hyperhomocysteinemia and impaired methylationare well-established and can negatively impact oocyte quality and embryo viability [19, 20], which is consistent with the lower pregnancy rates we observed at low B12 levels

However, increased fish demand due to the expansion of aquaculture, pressure on dwindling marine species, and marine pollution have prompted the search for alternative omega-3 PUFA sources (94)

Here, we introduced the functional efficacy and significant targets of natural herbs with their active compounds for treating PCOS through in vitro and in vivo studies with clinical trials