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Use a fresh sterile syringe and needle for each dose

Morning timing also aligns with your natural circadian rhythm of hunger hormones, which peak earlier in the day for most people

By binding to GLP-1 receptors in the hypothalamus, they reduce appetite and promote satiety, leading to significant weight reduction in clinical trialswith newer agents achieving approximately 15% weight loss in obesity without diabetes (semaglutide) and up to 21% (tirzepatide), with somewhat lower reductions typically seen in patients with type 2 diabetes

7 But Pendulum also uses proprietary strains, so the research on them is currently limited to studies funded by Pendulum itself