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Chronic ankle pain is often the result of tissue damage and inflammation from either chronic conditions or blunt trauma to the ankle

At 1mg weekly, average weight loss was 8.7% over 48 weeks

However, its important to note that 24 weeks, while substantial for clinical trials, represents a relatively limited timeframe for assessing lifetime exposure safety

More important than how much weight is lost, Drucker told CNN Friday, are the health benefits GLP-1 medicines have shown in studies, which include reduction of metabolic liver disease and sleep apnea and osteoarthritis and heart disease and strokes, which dont appear to be strictly weight-loss dependent. Even if next-generation medicines show greater degrees of weight loss, Drucker said, it takes several years for trials to prove benefits on other outcomes like those, which may be more meaningful to patients and doctors