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Dr Nomathemba Chandiwana, chief scientific officer at South Africas Desmond Tutu Health Foundation, and a specialist in obesity, who was not involved in the study, said: This could be very significant for South Africa and many African countries and low and middle-income countries [LMICs] at large where cost has been one of the main barriers to access. She said analysis suggested about 27% of adults worldwide met the criteria for drugs such as semaglutide and importantly, most of those live in LMICs where access to these medicines is extremely limited