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Oral (systemic) medication can include antibiotics, retinoids or hormonal agents (i.e

Bricogne, G

Furthermore, L-carnitine may also positively contribute to glucose homeostasis, through downregulating the gluconeogenic enzymes expression, including phosphoenolpyruvate carboxykinase (PCK1) and fructose-1,6-bisphosphatase isozyme 2 (FBP2), while upregulating the glycolytic enzymes expression, e.g., pyruvate kinase and glucokinase (10)

Transformingly, the original figure was transformed to be compared with the found results, demonstrated by total BACE1 expression of mBCEC from AST/Bex-treated 3xTg AD mice, that are lower than the BACE1 expression level in 3xTg AD mice and non-transgenic