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In GD, the major autoantigen (thyroid-stimulating hormone (TSH)-antibody) is to the receptor for the TSH, which causes overproduction of thyroid hormones, resulting in symptoms such as irritability, rapid heartbeat, weight loss, poor tolerance of heat and bulging eyes (Graves orbitopathy) ( Reference Effraimidis and Wiersinga 4 , Reference Marcocci, Kahaly and Krassas 7 , Reference Brent 8 )

NET-targeted therapy: effects, limitations, and potential strategies to enhance treatment efficacy

Clinical development ceased in 2003 with no products FDA approved, but melanotan II products are currently sold and purchased online

A meta-analysis of forty-three studies involving women with early-stage BC found a 33% increase in BC-related and overall mortality among women with obesity compared to their non-obese counterparts [14,15]