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Ceramide generation was a critical component of Fas receptor-induced eryptosis, whereas therapy with natural organosulfur compounds inhibited the apoptotic death of erythrocytes by antagonizing oxidative stress and the Gardos channel that led to suppression of ceramide-initiated Fas aggregation in lipid rafts of these erythrocytes

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Western blotting using an anti-cauxin antibody confirmed that the 70 kDa protein was cauxin (Figure 4C)

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