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Patients with type 2 diabetes who have established diabetic retinopathy at treatment initiation face the highest risk, particularly when experiencing rapid A1c reductions within the first 16 weeks of therapy

personal fees from Novo Nordisk a/s, Abbott Rapid Diagnostics a/s, outside the submitted work

GLP-1 drugs appear to downregulate inflammatory pathways, which may help stabilize plaques and reduce the likelihood of rupture (the event that can trigger heart attacks)

Tirzepatide, the dual GLP-1 and GIP receptor agonist marketed as Mounjaro, works by signaling your brain to reduce hunger while slowing stomach emptying