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A lot will depend on the severity and longevity of your B12 deficiency as to how long before there is no further improvement or recovery

Symptoms of vitamin B12 and folic acid deficiency anemia include: Shortness of breath Headache Indigestion Loss of appetite Heart palpitations Vision problems Feeling weak or tired Diarrhea Pain or redness of the tongue, sometimes with mouth sores Problems with memory, comprehension, and judgment (cognitive changes) Some of these symptoms may also occur in people who are deficient in vitamin B12 or folic acid but are not anemic

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Transdermal Patches Patches typically have higher bioavailability because they skip the digestive tract altogether