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Some early reports suggest that reducing dose frequency may help certain patients maintain weight loss, but experts also caution that microdosing itself is loosely defined and not supported by robust long-term data

JAMA 315 , 788800 (2016)

They are central to facial expression, speech and eating, and the vermilion border (the sharp edge between red lip and surrounding skin) is the single most visually scrutinised feature of lower face anatomy

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