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The western blot results demonstrated that Fer-1 treatment effectively inhibited the degradation of SLC7A11 and GPX4 and decreased the expression of COX2, indicating the inhibition of osteoblastic ferroptosis (Fig

SARS-CoV-2, the newly emerged RNA (29.9-kb) virus possess a unique genomic ability to insert and reprogram a mega-fold larger size human DNA (3.1-Mb) and its cellular metabolic machinery to prime, alter, and redirect host macro-molecules for its own life cycle

This process is canonically driven by the stabilization of PTEN-induced kinase 1 (PINK1) on the outer membrane of depolarized mitochondria, which subsequently recruits the E3 ubiquitin ligase Parkin (56)