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K., Hyeon, J

BMJ 385 , e078483 (2024)

The following side effects have been reported in subjects taking 3mg liraglutide for weight loss [24]: Nausea (39.3%) Diarrhea (20.9%) Constipation (19.4%) Vomiting (15.7%) Headache (up to 13.6%) Increases in mean resting heart rate (over 10% ) Less common side effects that occur in less than 10% of patients are: Dyspepsia Abdominal pain Gastroesophageal reflux disease Eructation Flatulence Dry mouth Elevated pancreatic enzymes Constipation Gastritis Abdominal discomfort Hypoglycemia Dizziness Hypotension Injection site reactions (pain, bleeding, redness, swelling, or itching) Rare but serious side effects include pancreatitis, gallbladder disease, cholestasis, and allergic reactions

1c), and an intracellular helical domain (ICH) that links TM6 of the N-terminal bundle and TM7 of the C-terminal bundle