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[4] As a result, GLP-1 agonists are contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or those with multiple endocrine neoplasia syndrome type 2 (MEN 2), a genetic disorder that increases the risk of certain types of tumors

Because glutamate released during neurotransmission is recycled via glutamine in glial cells, glutamine may index glutamate neurotransmission

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The highest dose produced weight loss comparable to liraglutide 3.0 mg, establishing cagrilintide as the first long-acting amylin analog to demonstrate clinically meaningful weight reduction in a randomized trial