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Metabolic and Appetite Regulation Explores the role of melanocortin signaling in energy balance, obesity, and appetite control

[1] [2] This peptide plays a crucial role in glucose homeostasis by stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying

They designed a 16-week prospective randomized open-label study with 30 men, with BMI 41.2 8.4 kg/m2 and aged 46.5 10.9 years

It is also an issue affecting patients who had started losing weight but then are not able to continue taking the medication and start to gain weight again, she says