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Extensive research has explored the impact of oral nutritional supplements, varying in composition and dosage, on the symptoms of DED

The influence of genotype on acclimatization has been demonstrated (Dolcet-Sanjuan et al

This oral preparation would offer a more convenient and comfortable option for patients, potentially leading to better treatment compliance.58,59 Overall, the future research direction of GLP-1RAs involves making them more similar to those in the human body, extending their duration of action, and creating oral formulations for easier administration.60,61 These advancements aim to improve patient experience, compliance, and treatment outcomes

Many studied probiotics land in the 1 to 20 billion CFU per day range, depending on strain and goal