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In addition, fewer Wegovy-treated patients experienced deterioration in NYHA functional class compared to those who were given placebo (2.09% versus 5.24%, respectively

If your B12 deficiency is caused by longterm vegetarianism/veganism, monthly injections are recommended

"Appetite, eating attitudes, and eating behaviours during treatment with retatrutide in adults with type 2 diabetes: Results of a phase 2 study." Diabetes, Obesity and Metabolism