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Antioxidants (Basel, Switzerland) , 10(2), 174
Injecting rats with selenium 24 hours prior to acetaminophen overdose provided significant protection against hepatotoxicity, lowered levels of ALT and AST (markers of liver damage), and increased liver glutathione levels (Schnell 1988)
These findings stress the importance of targeting mBzR/IMAC as a harbinger of more severe and permanent mitochondrial damage, which, through the ROS-induced ROS release mechanism, primes the opening of the PTP
4.3 Mitochondrial function CHAC1 plays a critical role in maintaining mitochondrial function and inducing ferroptosis under conditions of cysteine starvation in non-small cell lung cancer (NSCLC) cells
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