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Any combined use is based on theoretical pharmacology and individual drug studies rather than robust clinical evidence, making it an investigational approach

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An estimate of the final policy that includes the effects of estimated changes in enrollment, utilization, and case-mix based on the FY 2026 Mid-Session review budget approximates the estimated decrease in total payments at $290 million, with Medicare OPPS payments decreasing by $220 million and beneficiary copayments decreasing by $70 million in CY 2026

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Ma C, Lee JK, Mitra AR, et al