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By stimulating insulin secretion, suppressing glucagon release, and slowing gastric emptying, semaglutide helps lower blood sugar levels, which can positively impact cardiovascular health

The medication also helps lower the risk of kidney failure or the progression of chronic kidney disease in patients with existing kidney conditions and type 2 diabetes

The dramatic price reductions under the November 2025 MFN deals could also reduce patient abandonment driven by cost concerns

Importantly, these medications significantly slow gastric emptyingthe rate at which food moves from the stomach into the small intestinethough this effect may attenuate somewhat with continued use