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The consent must accurately characterize the compound as an unapproved bulk drug substance (not as an approved drug used off-label), the evidence base and its limitations, known and theoretical risks, alternatives considered, the monitoring plan, and the patients ability to decline or discontinue

Additionally, it occupies GIP receptors and mimics the action of the GIP hormone to enhance insulin release and promote fat breakdown

This leads to protein misfolding and impairs key enzymes involved in maintaining proteostasis, ultimately resulting in protein aggregation 65,66,67,68