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The agency is also making one notable change: the council of senior FDA leaders that initially weighed in on approval decisions will no longer be routinely required for applications

Individuals taking GLP-1s in this study reported lower subjective craving for alcohol, so it would be reasonable to think that these drugs could be helpful for those who have problems with alcohol, though larger studies are still needed. Why Might GLP-1s Affect How People Metabolize Alcohol

Studies have shown that significant concentrations of lixisenatide were found in the brain of mice 30 minutes and 3 hours after intraperitoneal injection, suggesting that lixisenatide could cross the BBB (125)

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