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How This Works Sermorelin is a synthetic analog of growth hormonereleasing hormone (GHRH) that binds to GHRH receptors on pituitary somatotropes, stimulating endogenous pulsatile GH secretion [1]

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GLP-1 degradation Native GLP-1 has a very short half-life, which, depending on the species, is around 12 min [[182], [183], [184]] and results from two causes: (a) the action of the enzyme dipeptidylpeptidase-4 (DPP-4) and (b) renal elimination