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Reactive oxygen species (ROS) and dysregulated iron homeostasis promote oxidative stress and immune dysregulation through activation of the NF-B pathway, impairing macrophage phagocytic activity and contributing to resistance to ferroptosis (68)

53 Exercise Intensity: Start with lower-intensity activities and gradually increase as tolerated

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In contrast to the kidney, the liver has relatively less reserve pools of analytes to recover flux through these pathways, and thus energy production