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In the case of PTGS2, the key amino acids are ARG513, PHE518 and ILE617
Figure 2: Changes in body weight from baseline to the end of treatment at week 26 associated with the treatment policy estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo
Moreover, the depletion of Leu and isoleucine (iLe) induces T cells to enter the S-G1 phase, which then stops dividing and expires
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