The staff of Mother Jones is, once again, rounding up the heroes and monsters of the past year
SURMOUNT-2: tirzepatide with type 2 diabetes The second trial focused on adults who had both obesity and type 2 diabetes, a population that traditionally loses less weight with GLP-1 medications because insulin resistance and metabolic dysfunction create additional barriers
Thats what happened to 45-year-old Mark, a construction supervisor
Within hours after cleaning, teeth become coated with a layer of salivary proteins, which can isolate antibacterial materials from bacteria, thereby reducing antimicrobial efficiency and long-term efficacy ( In addition to the two aforementioned oral-specific environmental resistance factors, the clinical translation of nanomaterials currently faces several challenges:(1) the long-term biosafety, biocompatibility, and functional durability of these nanomaterials within the oral cavity require rigorous assessment in live animal models and, ultimately, clinical trials (Sajithkumar et al., 2025)