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and v) in the rats, which underwent delayed therapy, at 48 h postL-NAME administration: immediately before medication ( A ) and after application ( B , C , D , E , F , and G ), immediately after ( B ), and after 1 and 2 days, corresponding to day 3 (C) and day 4 ( D ) L-NAME time, and at the days 7 ( E ), 14 ( F ), and 28 ( G ) L-NAME time

Second, the preservative extends the shelf life of the solution, allowing you to use it for your research over a period of several weeks without worrying about contamination

To understand the long-term safety and chronic effectiveness of these treatments, these studies will be essential