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Identify and Address Triggers The first step is to identify what's causing your mast cells to become hyperactive: Test for hidden infections : Comprehensive testing for tick-borne diseases, viral infections, and parasites Evaluate for mold exposure : Environmental testing and mycotoxin testing Assess toxic burden : Testing for heavy metals and other environmental toxins Check for connective tissue issues : Evaluation for hypermobility and EDS Consider genetic testing : Looking for variants that affect mast cell function and histamine metabolism 2

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the 1 mg arm is the lowest measured human pharmacologic activity: Frias Lancet 2018

HIF: hypoxia-inducing factor