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Real-world example: A backyard barbecue or beach day where drinking happens over several hours in direct sun combines two separate dehydrating forces at once heat and alcohol making this one of the more realistic everyday scenarios where the BAC-concentrating effect is likely to be more than trivial

The culmination of all of these studies come to light with the finding of several (some reported and many from our group still publication pending) Larons Syndrome (congenital IGF-1 deficiency or GH insensitivity) never treated patients who underwent progression to MetS and ultimately to T2D together with diabetic retinopathy when they reached their late 30 s, [250, 251]