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Research has also shown that chronic infections, including bacterial infections, that may interrupt the gut microbiome, can also increase the risk of blood clotting ( 7 , 8 , 9 , 10 , 11 )

However, it's important to note that for pernicious anaemia or deficiency with neurological involvement, intramuscular hydroxocobalamin injections remain the first-line treatment in the UK, as recommended by NICE and the British Society for Haematology

Its also recommended to be cautious in people on certain medications like levodopa (without carbidopa), as mentioned, or those with specific medical conditions, but these are matters of caution rather than strict contraindications

Those with a stressful lifestyle and/or profession