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doi: 10.1016/j.carbon.2015.06.030

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To some extent, there is a contradiction between the protective effect of soluble UA as an antioxidant and its positive relation with MMP-8 et al

Studies have shown that the accumulation of heavy metals, which are stored mainly in fat, might be a significant contributor to obesity which makes us overweight in the first place.(2) When weight loss is very rapid, the levels of toxins and heavy metals released from fat back into blood circulation can overwhelm our ability to remove them from our bodies (detoxification)