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For example, in the CREDENCE trial (Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation trial), the residual risk of the primary composite outcome event of ESKD, doubling of serum creatinine, or renal or CV death with canagliflozin was 11.1% [11, 14]

Results will vary based on your genetics, age, and overall health status

The two are at different levels of evidence, which is something to be aware of in practical considerations