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When used as medication, GLP-1 RAs increase insulin production when blood sugar is high, reduce the amount of glucagon (a hormone that raises blood sugar), slow digestion, and increase feelings of fullness

Growing evidence indicates that dietary herbs can modulate gut microbiota composition and generate bioactive metabolites that mitigate inflammation, oxidative stress, and apoptosis following stroke, underscoring a promising gut-mediated mechanism for herbal interventions (Li X

Recent advances in single cell and nuclei RNA sequencing approaches greatly improved our understanding of cellular maladaptations in AT dysfunction and outdated the historical notion that only two macrophage subpopulations (M1 as pro-inflammatory and M2 as anti-inflammatory macrophages) exist 19,20