The average 7-12 year delay from symptom onset to diagnosis reflects systemic failures in medical education, clinical assessment, and healthcare system organization rather than inherent limitations of medical knowledge or technology
Furthermore, the immunohistochemistry analysis evaluated the protective effects of the Au-PX-PLGA on dopaminergic neurons in the striatum and tyrosine hydroxylase, which is an essential enzyme in dopamine synthesis, served as the biomarker for dopaminergic neuron integrity
Satoh K, Kitahara A, Soma Y, Inaba Y, Hatayama I, Sato K (1985) Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis
The length of SmGSTs ranged from 216 bp to 672 bp