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Shah S, Dhawan V, Holm R, Nagarsenker MS, Perrie Y, Liposomes

In patients with micrognathia (small jaw) or retrognathia, the chin is posteriorly displaced causing the tongue to fall backward toward the posterior pharyngeal wall

The cells were then washed once in ice-cold PBS, trypsinized, pelleted, and then homogenized in mitochondrial isolation buffer (0.21 M mannitol, 0.07 M sucrose, 0.1 mM EDTA, 1 mM EGTA, 10 mM Tris HCl, 0.5% BSA, pH 7.4 using KOH)

We think of this as a form of metabolic whiplash, and our data suggest it is detrimental to heart health. The study also shines light on the affordability, and lack of insurance coverage, for weight-loss drugs