In this blog post, BPS President @KarenFlemingPhD amplifies the remarkable story of how a molecule discovered in lizard venom ultimately led to today's groundbreaking GLP-1 drugs
Protease-Independent Metabolic Effects of DPP-4 While some of the effects of DPP-4and, arguably, most, if not all of the pharmacological effects of DPP-4 inhibitors (38)on glucose homeostasis are mediated primarily by modulating the activity of the incretin hormones, it has also been proposed that DPP-4 may influence metabolic control via mechanisms which do not necessarily involve its catalytic activity, with several studies noting a positive correlation between DPP-4 and insulin resistance (79, 81, 88)
Drawing conceptual inspiration from peptide studies involving compounds such as CJC-1295 Ipamorelin, the stack focuses on creating an internal environment conducive to anabolic signaling, recovery processes, and metabolic efficiency
Some forms also come as oral capsules, but the most studied method remains injectable
