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Although many hormones increase the glucose level in blood and exert mutual compensatory effects, insulin is the only blood glucose-lowering hormone that is indispensable for maintaining regular blood glucose levels, indicating an essential role of pancreatic islet homeostasis in blood glucose control

Arias-Barrau, E., Dirusso, C.C

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Despite this improvement, the most recent brain MRI still showed diffuse cerebral and cerebellar atrophy, and the patients overall prognosis remained poor