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Although global Thbs1 KO mice show significant defects in host defense during acute PA pneumonia when compared to WT mice 19,32 , a more modest phenotype was observed in PF4 C re Thbs1 flox KO mice, suggesting that additional cellular sources of TSP1 contribute to pulmonary host defense
This is the substance that makes the skin look darker
In addition, the predictive performance of the final model was assessed by prediction-corrected visual predictive check (VPC) plots
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