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Original Study Reference Kuceki G, Coppinger AJ, Ragi SD, Johnson LS, Goren A, Kalil LL, Cirino P, Wambier CG

and 4) Oxidative stress and NO bioavailability, since age-related oxidative stress and downregulation of endothelial nitric oxide synthase (eNOS) impair the bioavailability of NO[293], which is likely to contribute to decreased microvascular density

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