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In addition, variable levels of caspase 4 related to ER stress was found as well as no significant differences between the expression of genes relating to ER stress between untreated patients and normal controls, eliminating the possibility that ER stress is involved in apoptotic cell death in Fabry PBMCs

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Retinal anatomy Immediately after behavioral and/or physiological assessment, a subset of exposed larvae (N = 3 per treatment for each exposure age and postexposure timepoint) were euthanized in 0.02% tricaine and fixed in 4% paraformaldehyde, followed by 70% ethanol, for anatomical analysis